TheorphanreceptorNur77bindscytoplasmicLPSto activate the

nuri77Distinguishing true Ag-stimulated lymphocytes from bystanders activated by the inflammatory milieu has been difficult. Nur77 is an immediate early gene whose expression isOverview of the antiinflammatory snaling pathway of the orphan nuclear receptor Nur77 in EC. LPS induces an increase of Nur77 expression that negatively regulates endothelial