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apo 388APO388 is a novel compound that has emerged as a result of extensive research into various medical conditions, particularly those involving…combination of alleles at rs429358 and rs7412 variants, an individual could possess one of six common APOE genotypes (e4e4, e4e3, e4e2,e3e3, e2e3 and e2e2, appendix p 6 table